Table 2

Serum Aβ40 levels of homozygous and hemizygous APP21 and APP31 lines determined by ELISA. h?: homozygosity status not determined; he:hemizygous; ho: homozygous; SE: Standard error; N: number of rats included in the statistical test; P: P value. All rats in the APP21 line had measurable levels of Aβ40 in serum. The Aβ40 levels were out of range in 10 of 20 rats in the APP31 line.

40 (pg/ml)

SE

N

Age, d

P


APP21 h?

466.2A

46.2

9

61

<.0001

APP21 he

298.2A

34.7

16

151 ± 81

<.0001

APP21 ho

486.0A

98.0

2

70

<.0001

APP31 h?

93.2B

33.6

17

81 ± 42

0.0083

APP31 ho

0.0B

80.0

3

107

1


Agca et al. BMC Neuroscience 2008 9:28   doi:10.1186/1471-2202-9-28

Open Data