Table 2

Serum Aβ40 levels of homozygous and hemizygous APP21 and APP31 lines determined by ELISA. h?: homozygosity status not determined; he:hemizygous; ho: homozygous; SE: Standard error; N: number of rats included in the statistical test; P: P value. All rats in the APP21 line had measurable levels of Aβ40 in serum. The Aβ40 levels were out of range in 10 of 20 rats in the APP31 line.

Aβ40 (pg/ml)
 SE
 N
 Age, d
 P
APP21 h?
 466.2A
 46.2
 9
 61
 <.0001
APP21 he
 298.2A
 34.7
 16
 151 ± 81
 <.0001
APP21 ho
 486.0A
 98.0
 2
 70
 <.0001
APP31 h?
 93.2B
 33.6
 17
 81 ± 42
 0.0083
APP31 ho
 0.0B
 80.0
 3
 107
 1

Agca et al. BMC Neuroscience 2008 9:28   doi:10.1186/1471-2202-9-28