Table 3

Antibody pattern in microvillous cells

TrpM5a Type MV cells

TrpM5b Type MV cells

Non-TrpM5 Type MV cells

Ciliated ORNs

Other tissue controls


TrpM5

+++

+++

-

+*

-

Calbindin

-

-

?

++

Calretinin

-

-

?

++

Chromogranin A

-

-

-

-

some cells in VNO

CK18

-

-

++

-

Espin

+++

+++

+++

-

CGRP

no contact

no contact

?

no contact

contact to SCCs

Gq/11

-

-

++

-

IP3R3

-

-

+++

-

Na+, K+-ATPase

-

-

-

-

nerve fibers, olfactory bulb

NSE

-

-

?

++

OMP

-

-

?

+++

P2X2

-

-

-

-

+ **

P2X3

-

-

+

+

PDE2A

-

-

+

++***

PGP9.5

-

-

?

+++

PLC beta2

-

-

+

+

Substance P

no contact

no contact

?

no contact

contact to SCCs

SNAP 23

-

-

?

-

synapses in muscle tissue

SNAP 25

-

-

?

-

synapses in muscle tissue

SUS-1

-

-

-

-

supporting cells

SV2

-

-

++

-

nerve fibers, synapses in various tissues

Synaptophysin

-

-

++

++

TrpC6

-

-

++***

-

VAChT

-

-

-

-

+ in SCCs

Villin

+++

+++

+++

-


+++ = abundant; ++ = some; + = few; - = absent; ? = possible but not confirmed by electron microscopy

MV = microvillous cells

* weakly expressed in some ORNs in limited areas

** P2X2 positive cells are present in the thin epithelium of the turbinates which resemble solitary chemosensory cells (SCCs)

*** in limited areas

Hansen and Finger BMC Neuroscience 2008 9:115   doi:10.1186/1471-2202-9-115

Open Data