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Open Access Highly Accessed Research article

Left inferior frontal gyrus is critical for response inhibition

Diane Swick12*, Victoria Ashley1 and And U Turken1

Author Affiliations

1 Research Service, Veterans Affairs Northern California Health Care System, Martinez, CA 94553, USA

2 Department of Neurology, University of California, Davis, Martinez, CA 94553, USA

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BMC Neuroscience 2008, 9:102  doi:10.1186/1471-2202-9-102

Published: 21 October 2008

Additional files

Additional file 1:

Lesion Reconstructions for LIFG Patients. Lesion reconstructions for the individual patients with lesions of the left inferior frontal gyrus (LIFG). Lesions were estimated from MRI or CT scans and transcribed onto sequential axial templates derived from the MNI brain. Lesions are shown from ventral to dorsal.

Format: TIFF Size: 4.3MB Download file

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Additional file 2:

Lesion Reconstructions for OFC Patients. Lesion reconstructions for the individual patients with lesions of the orbitofrontal cortex (OFC). Lesions were estimated from MRI or CT scans and transcribed onto sequential axial templates derived from the MNI brain. Lesions are shown from ventral to dorsal.

Format: TIFF Size: 2.6MB Download file

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Additional file 3:

Full List of References for the ALE Meta-Analysis. Thirty-nine papers were found to meet the criteria for inclusion in the Activation Likelihood Estimation analysis of response inhibition conditions in Go/NoGo and Stop-Signal tasks: 25 papers were downloaded from the BrainMap database, and 14 were found through PubMed searches.

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Additional file 4:

Averaged LIFG Lesion Reconstruction and ALE Map. Both are illustrated on axial templates that are matched for slice angle. (A) Lesion overlap in patients with damage to the left inferior frontal gyrus. (B) Activation likelihood estimation (ALE) map showing significant inhibition-related activations.

Format: TIFF Size: 998KB Download file

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