OECs in the neonatal olfactory system in vivo do not express calponin. The schematic in Figure 1 illustrates the histology of the olfactory mucosa (OM). The OM can be divided into two parts, the olfactory epithelium (OE) and the lamina propria (LP). The OE contains mature and immature olfactory receptor neurons (ORNs) and their support cells (sustentacular cells) and two types of potential stem cells; globose basal cells and horizontal basal cells. The LP contains extensions of ORN axons which are ensheathed by OECs. Supporting the glia and axons in the LP is loose connective tissue which contains fibroblasts, Bowman glands and blood vessels. A-B) Calponin did not colocalise with an ORN marker (TUJ1 positive-red, calponin-green and DAPI-blue). Figure 1B is a higher magnification of the boxed area in Figure 1A. Calponin did not colocalise with OECs as defined by expression of C) p75NTR (p75NTR -red, calponin-green, DAPI-blue) or D, E, F) S100 (S100-red, calponin-green, DAPI-blue, * nerves). Figure 1F is a higher magnification of Figure 1E. All images were obtained using confocal microscopy.
Tomé et al. BMC Neuroscience 2007 8:74 doi:10.1186/1471-2202-8-74