Table 2

Functional effects of pAMICDYS and pAVP22-MICDYS for diaphragm muscles though intraperitoneal injection

C57BL/10

mdx

pAVP22

pAMICDYS

pAVP22-MICDYS


(n = 4)

(n = 4)

(n = 3)

(n = 5)

(n = 5)


BM (g)

20.3 ± 1.5

23.8 ± 1.6

22.5 ± 1.5

23.3 ± 1.3

21.8 ± 1.6

sP0 (KN/m2)

215 ± 6.3

90.8 ± 4.3

92.1 ± 5.1

98.7 ± 5.8

145.3 ± 6.9*


Values are means ± SEM; n, number of mice; BM, body mass; sPo, specific maximum isometric tetanic force.

* P < 0.05 versus untreated mdx and treated by pAMICDYS.

Xiong et al. BMC Neuroscience 2007 8:50   doi:10.1186/1471-2202-8-50

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