Table 1

The incidence of apoptosis in the AVPV of adult male Long-Evans ratsa

Group
Total Cell Number
Apoptotic Cell Number
Incidence of Apoptosisb

Phyto-free
126
3
2.4

125
1
0.8

113
6
5.3

133
8
6.0

120
4
3.3

123.4 ± 3.3
4.4 ± 1.2^
3.6 ± 1.0^
Phyto-600
111
32
28.8

112
34
30.1

108
41
38.0

124
40
32.3

125
45
36.0

116.0 ± 3.5
38.4 ± 2.4
33.1 ± 1.7

a The rats were exposed to either a soy isoflavone-free diet (Phyto-free) or a soy isoflavone-rich diet (Phyto-600) from conception until 150 days of age (n = 5 per diet treatment group).

b Incidence of apoptosis was expressed as the percentage of apoptotic cell number over total cell number in AVPV.

^ Significantly greater apoptotic cell number or incidence of apoptosis in the Phyto-600 AVPV compared to the Phyto-free group (p < 0.05; two sample student t-test).

Bu and Lephart BMC Neuroscience 2007 8:13   doi:10.1186/1471-2202-8-13