Table 1 |
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Gp120 reduced astroglial cell viability as expressed by % trypan blue positive cell counts in 10 experiments. NAC (0.5–5 mM) antagonized this effect. |
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TREATMENT |
% dead cells |
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|
|
CTRL |
2 ± 1.3 |
|
Gp120 100 pM |
16 ± 1.4* |
|
Gp120 1 nM |
38 ± 2* |
|
Gp120 10 nM |
45 ± 3.2* |
|
Gp120 10 nM + NAC 0.5 mM |
40 ± 2.4§ |
|
Gp120 10 nM + NAC 1 mM |
22 ± 2.1§ |
|
Gp120 10 nM + NAC 5 mM |
6 ± 2§ |
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P < 0.05 gp120-treated astrocytes vs control (CTRL) § P < 0.05 NAC vs gp120-treated astrocytes |
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Visalli et al. BMC Neuroscience 2007 8:106 doi:10.1186/1471-2202-8-106 |
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