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Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens

YueMei Zhang and Bhagu R Bhavnani*

BMC Neuroscience 2006, 7:49  doi:10.1186/1471-2202-7-49