A series of voltage-activated current traces of B1, B2, B4 motoneurons evoked by 5 mV depolarizing voltage steps between -60 mV and +40 mV. A. From a holding potential of -40 mV, initial fast inward current (seen on B2 and B4) is followed by a slowly activating outward current (B1, B2, B4 cells) which does not inactivate during the 50 ms current step. B. The same voltage protocol starting from -80 mV holding potential evokes an additional, fast outward current component on all three motoneurons. C. Subtracting the two current records shows the initial transient outward current is a fast inactivating outward current during the course of the 50 ms voltage steps. All experiments in normal saline.
Vehovszky et al. BMC Neuroscience 2005 6:70 doi:10.1186/1471-2202-6-70