Figure 4.

Wallerian degeneration proceeds in retrograde direction along individual axons after crush injury. Confocal composite picture showing seven consecutive lengths (from top to bottom in overview) of the proximodistal course of an individual YFP labelled axon within a peripheral nerve stump 44 h after crush injury displaying a retrograde progression of axon fragmentation. Note that this axon has fragmented in its distal end (lower inset) but not in its proximal end (upper inset). Axonal fragments are clearly demarcated by fluorescence interruptions (arrows in lower inset). YFP fluorescence has been pseudo-coloured yellow with the applied confocal imaging software (Biorad LaserSharp 2000). Scale bar: 500 μm

Beirowski et al. BMC Neuroscience 2005 6:6   doi:10.1186/1471-2202-6-6
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