Table 1

Allelic series of lin-12 mutants. Vulval phenotype abbreviations are as follows: Pvl, protruding vulva; WT, wild type; Vul, vulvaless; and Muv, multiple pseudovulvae. All animals were tested at 25°C except animals carrying the cold-sensitive lin-12(n137n460) allele were raised at the non-permissive temperature 15°C. Control animals raised at 15 or 25°C had wild type reversal rates (see Figs. 1 and 2).

strain

vulval phenotype

reversals/3 min. ± S.E.M.

n


lin-12(n941) (null)

Pvl

17.3 ± 1.7

15

lin-12(n941)/+

WT

10.8 ± 1.5

15

lin-12(+)

WT

10.5 ± 0.7

45

lin-12(n302)/lin-12(n941)

Vul

9.3 ± 1.3

15

lin-12(n302)

Vul

8.8 ± 1.1

13

lin-12(n379)

Vul

7.7 ± 0.5

15

lin-12(n676)

Vul

6.0 ± 0.3

5

lin-12(n137n460)/lin-12(n941)

WT

22.9 ± 1.5

12

lin-12(n137n460)/+

WT

20.1 ± 1.8

9

lin-12(n137n460)

Muv

23.7 ± 1.8

12

lin-12(n137)/lin-12(n941)

Muv

17.6 ± 1.2

5

lin-12(n137)/+

Muv

6.0 ± 1.6

7

lin-12(n427)

Muv

3.9 ± 0.2

15

lin-12(n137)

Muv

3.6 ± 1.1

10


Chao et al. BMC Neuroscience 2005 6:45   doi:10.1186/1471-2202-6-45

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