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Effect of 6 h SD on sleep time and delta power in cry1,2+/+ and cry1,2-/- mice. |
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| NREMS amount [min] |
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| baseline |
post-SD |
difference |
|
| cry1,2+/+ |
264 ± 9 |
297 ± 15# |
33 ± 8 |
| cry1,2-/- |
312 ± 9* |
318 ± 9 |
5 ± 4* |
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| NREMS bout duration [min] |
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|
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| baseline |
post-SD |
difference |
|
| cry1,2+/+ |
2.6 ± 0.1 |
3.3 ± 0.3# |
0.7 ± 0.3 |
| cry1,2-/- |
4.2 ± 0.4* |
3.7 ± 0.2 |
-0.4 ± 0.3* |
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| NREMS Delta power [μV2/0.1 Hz] |
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| baseline |
post-SD |
difference [%] |
|
| cry1,2+/+ |
407 ± 59 |
704 ± 125# |
170 ± 14 |
| cry1,2-/- |
619 ± 67* |
805 ± 40# |
134 ± 8* |
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| REMS amount [min] |
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|
|
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| baseline |
post-SD |
difference |
|
| cry1,2+/+ |
52 ± 6 |
63 ± 3# |
11 ± 7 |
| cry1,2-/- |
53 ± 4 |
58 ± 1 |
5 ± 3 |
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Post-hoc comparisons: * P < 0.05 vs. wild type, unpaired t-test; # P < 0.05, vs. baseline day, within same genotype, paired t-test. Delta power was calculated over the first hour after the SD (ZT6-ZT7). REMS and NREMS amount and bout duration were calculated over 12 hours (ZT6-ZT18). Differences indicate mean individual post-SD – baseline differences except for delta power which is calculated as percentage of baseline. | |||
Wisor et al. BMC Neuroscience 2002 3:20 doi:10.1186/1471-2202-3-20 |
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