Table 2

Brain regions showing significant correlations with tic severity
Anatomical location Cluster MNI-space t-value p-value
(voxel) x y z (SVC)
FA negative correlation
L superior frontal gyrus 1394 −15 51 19 6.29 0.008
L cingulate gyrus 291 −10 16 46 4.19 0.010
R middle occipital gyrus 119 44 −76 −2 3.81 0.024
R middle frontal gyrus 186 28 43 4 3.69 0.031
R thalamus (VPL) 71 20 −21 −4 3.65 0.033
R cingulate gyrus 28 24 38 16 3.52 0.044
L medial frontal gyrus 22 −13 −8 61 3.48 0.045
R medial frontal gyrus 12 9 −25 67 3.46 0.051
FA positive correlation
R superior temporal gyrus 92 54 −7 −2 4.36 0.001
L lingual gyrus 627 −19 −67 −11 4.04 0.014
L parahippocampal gyrus −29 −53 −4 3.96 0.017
R cingulate gyrus 75 5 22 32 3.92 0.019
R superior temporal gyrus 345 43 −23 9 3.78 0.025
L postcentral gyrus 123 −41 −23 47 3.69 0.031
L corpus callosum (body) 306 −17 −6 31 3.67 0.032
L thalamus 131 −11 −9 13 3.66 0.033
R medial frontal gyrus 25 7 40 −11 3.61 0.037
ADC positive correlation
L Putamen 2185 −26 4 −4 4.39 0.006
R Putamen 1192 28 2 −5 4.29 0.007
L precentral gyrus 297 −52 7 10 3.85 0.021
R putamen 190 21 18 4 3.75 0.026
L middle occipital gyrus 143 −50 −58 −11 3.71 0.026
L anterior cingulate gyrus 49 −9 44 6 3.65 0.031
L caudate body 109 −19 4 20 3.59 0.036
R precentral gyrus 27 43 3 10 3.57 0.038
L cingulate gyrus 51 −7 −20 29 3.56 0.038
R medial frontal gyrus 56 11 50 5 3.54 0.040
R middle frontal gyrus 19 29 50 −10 3.48 0.045
L Thalamus (VA) 17 −9 −2 9 3.42 0.051

Müller-Vahl et al.

Müller-Vahl et al. BMC Neuroscience 2014 15:6   doi:10.1186/1471-2202-15-6

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