Table 1

Mean ± S.D and independent t-test for HSP-70, GABA, serotonin, dopamine, oxytocin, and Interferon μ inducible protein 16 (IFI16) in neurointoxicated, Co Q protected and treated rat pups compared to healthy control
Parameters Group N Mean ± S.D. P value
HSP70 (ng/ml) Control 8 10.563 ± 0.370
PA 8 9.400 ± 0.490 0.001a
CoQ-Protected group 6 10.050 ± 0.404 0.030a
CoQ-treated group 8 10.033 ± 0.427 0.029a
GABA (ng/10 mg) Control 8 109.100 ± 4.666
PA 8 67.183 ± 3.125 0.001a
CoQ-Protected group 6 95.417 ± 4.529 0.01a
CoQ-treated group 8 85.079 ± 4.832 0.01a
Serotonin (ng/ml) Control 8 0.073 ± 0.017
PA 8 0.047 ± 0.011 0.004a
CoQ-Protected group 6 0.095 ± 0.018 0.043a
CoQ-treated group 8 0.097 ± 0.018 0.033a
Dopamine (ng/ml) Control 8 136.250 ± 18.468
PA 8 106.875 ± 12.229 0.002a
CoQ-Protected group 6 169.167 ± 24.580 0.014a
CoQ-treated group 8 160.000 ± 22.583 0.051a
Oxytocin (Pg/ml) Control 8 89.750 ± 4.464
PA 8 84.500 ± 4.751 0.039a
CoQ-Protected group 6 95.667 ± 4.967 0.037a
CoQ-treated group 8 95.000 ± 3.742 0.038a
Interferon μ inducible protein 16 (Pg/ml) Control 8 833.750 ± 63.906
PA 8 768.750 ± 53.033 0.044a
CoQ-Protected group 6 931.667 ± 77.567 0.024a
CoQ-treated group 8 983.333 ± 60.222 0.001a

aSignificant level between the studied groups compared to control when P < 0.05.

Al-Ghamdi et al.

Al-Ghamdi et al. BMC Neuroscience 2014 15:34   doi:10.1186/1471-2202-15-34

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