Table 3

Median histopathologic scores for the lung and heart tissues from each group
Control group Day 1 group Day 2 group Day 7 group p value
n = 7 n = 7 n = 7 n = 7
Lung
Interstitial edema 0 (0 – 1) 1 (1 – 2) 1 (1 – 2) 2 (2 – 3) <0,001
Hemorrhage 1 (0 – 1) 2 (2 – 2) 2 (2 – 2) 3 (2 – 3) <0,001
Epithelial injury 0 (0 – 1) 1 (1 – 2) 1 (1 – 2) 2 (1 – 2) <0,001
Hyalin membrane formation 0 (0 – 0) 1 (1 – 1) 1 (1 – 2) 2 (1 – 2) <0,001
Neutrophil infiltration 0 (0 – 1) 2 (1 – 2) 2 (1 – 2) 2 (2 – 3) <0,001
Emphysematous changes 0 (0 – 1) 1 (1 – 2) 2 (1 – 2) 2 (2 – 3) <0,001
Lymphocytic infiltration 1 (0 – 1) 1 (1 – 2) 2 (1 – 2) 2 (1 – 2) 0,017
Total injury score 2 (1 – 4) 9 (8 – 13) 11 (9 – 13) 15 (11 – 18) <0,001
Heart
Myocardial edema 0 (0 – 0) 1 (1 – 2) 1 (1 – 2) 2 (2 – 2) <0,001
Myocytolysis 0 (0 – 1) 1 (1 – 2) 2 (1 – 2) 3 (3 – 3) <0,001
Focal hemorrhage 0 (0 – 1) 1 (1 – 2) 2 (1 – 2) 3 (3 – 3) <0,001
Leukocytic infiltration 0 (0 – 0) 1 (0 – 2) 1 (1 – 2) 2 (1 – 2) <0,001
Loss of cross striation 0 (0 – 0) 1 (1 – 1) 1 (1 – 1) 2 (1 – 2) <0,001
Total injury score 0 (0 – 2) 5 (4 – 9) 7 (6 – 8) 11 (10 – 12) <0,001

Median (Min - Max).

Açıkgöz et al.

Açıkgöz et al. BMC Neuroscience 2014 15:33   doi:10.1186/1471-2202-15-33

Open Data