Table 4

Summary of the variations from striatum metabolites in mice
Metabolites Chemical shift Control-nicotine
(ppm) VIPa Loadingb
Cystine 3.36 10.51 -0.76
Glucose 3.40 5.97 -0.43
Glutamate 2.08 3.37 -0.18
Acetoacetic acid 3.44 2.02 -0.124
Tryptophan 3.48 1.92 -0.138
Lysine 1.36 1.91 ±0.03
Taurine 3.28 1.54 -0.08
Creatine 3.04 1.49 ±0.088
Acetylcholine 3.24 1.36 ±0.054
NAA 4.4 1.36 ±0.095

aVariable importance in the projection (VIP ≥ 1) was obtained from OSC-PLS.

bLoading: the positive (+) value represents an increase of the metabolite in the second group of the subtitle (e.g.: Control → Nicotine), while the negative(-) value represents a decrease of the metabolite in the second group of the subtitle.

Li et al.

Li et al. BMC Neuroscience 2014 15:32   doi:10.1186/1471-2202-15-32

Open Data