Table 2

Summary of the variations from NAc metabolites in mice
Metabolites Chemical shift Control-nicotine
(ppm) VIPa Loadingb
Glutamate 2.08 5.02 +0.369
Isoleucine 1.28 4.46 +0.331
1 -Methyihistamine 3.68 2.99 +0.223
Cystine 3.36 2.96 +0.068
2-Ketobutyric acid 2.76 2.24 +0.162
Lactate 1.32 2.11 +0.148
Tryptamine 7.32 2.09 +0.155
Glycerol 3.64 2.04 +0.153
Glucose 3.40 1.92 +0.066
3 -Hydroxybutyric acid 1.20 1.90 +0.142

aVariable importance in the projection (VIP ≥ 1) was obtained from OSC-PLS.

bLoading: the positive (+) value represents an increase of the metabolite in the second group of the subtitle (e.g.: Control → Nicotine).

Li et al.

Li et al. BMC Neuroscience 2014 15:32   doi:10.1186/1471-2202-15-32

Open Data