Table 1

Physiological variables
Group
Control (n = 6) UCO (n = 3) BCO (n = 4) BCOH (n = 4)
Body weight (kg) 19.5 ± 2.8 17.3 ± 2.3 22.8 ± 3.3 22.0 ± 3.4
HR (beats/min)
Before carotid ligation 125 ± 15 112 ± 11 122 ± 21 112 ± 25
At brain biopsy 111 ± 15 115 ± 9 103 ± 15 138 ± 16ab
MAP (mmHg)
Before carotid ligation 101 ± 14 92 ± 4 105 ± 6 99 ± 17
At brain biopsy 94 ± 11 85 ± 9 89 ± 18 42 ± 7ab
Arterial pH (mmHg)
Before carotid ligation 7.50 ± 0.01 7.40 ± 0.01 7.53 ± 0.03 7.49 ± 0.06
At brain biopsy 7.49 ± 0.02 7.52 ± 0.02 7.55 ± 0.04 7.39 ± 0.01ab
Arterial pO2 (mmHg)
Before carotid ligation 107.2 ± 27.1 116.0 ± 48.1 98.3 ± 30.1 76.8 ± 11.6
At brain biopsy 100.0 ± 15.0 120.0 ± 50.5 82.7 ± 7.3 71.7 ± 9.8
Arterial pCO2 (mmHg)
Before carotid ligation 38.8 ± 6.1 38.3 ± 7.6 41.0 ± 6.5 38.1 ± 6.3
At brain biopsy 35.0 ± 8.0 37.0 ± 1.4 36.3 ± 4.6 41.3 ± 7.0
Esophageal temperature (ºC)
Before carotid ligation 39.3 ± 1.0 39.5 ± 1.0 38.3 ± 0.6 38.6 ± 0.9
At brain biopsy 39.4 ± 0.9 39.0 ± 1.2 38.0 ± 0.7 37.8 ± 0.7

BCO, bilateral carotid occlusion; BCOH, bilateral carotid occlusion with systemic hypotension; MAP, mean arterial blood pressure; UCO, unilateral carotid occlusion. Values are mean ± SD. ap < 0.05 vs. before carotid ligation; bp < 0.05 vs. control.

Suchadolskiene et al.

Suchadolskiene et al. BMC Neuroscience 2014 15:2   doi:10.1186/1471-2202-15-2

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