The spine loss of pyramidal neurons in HE rats. The spine density on layer V (A) pyramidal neurons of the primary sensorimotor cortex and hippocampal CA1 (B) pyramidal neurons was analyzed. Representative micrographs of basal segment and distal apical segment of dendrite were illustrated in A and B. Spine density was measured and analyzed in C and D. *, p < 0.05 between the mark and control rats. Bar = 10 μm for all photograph.
Chen et al. BMC Neuroscience 2014 15:15 doi:10.1186/1471-2202-15-15