Open Access Highly Accessed Research article

Genes showing altered expression in the medial preoptic area in the highly social maternal phenotype are related to autism and other disorders with social deficits

Terri M Driessen1*, Brian E Eisinger1, Changjiu Zhao1, Sharon A Stevenson1, Michael C Saul1 and Stephen C Gammie12

Author Affiliations

1 Department of Zoology, University of Wisconsin-Madison, Madison, WI, USA

2 Neuroscience Training Program, University of Wisconsin-Madison, Madison, WI, USA

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BMC Neuroscience 2014, 15:11  doi:10.1186/1471-2202-15-11

Published: 14 January 2014

Additional files

Additional file 1:

Complete list of all MPOA microarray target genes, nominal p-values, and fold changes.

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Additional file 2:

All genes relating to ASD, BPD, depression, and schizophrenia identified in significant microarray results.

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Additional file 3:

List of all miRNAs significantly linked to microarray genes with a p < 0.05. In the list, if a dash separates two letters, it indicates all miRNAs within those letters (e.g. MIR-30A-E indicates MIR-30A, MIR-30B, MIR-30C, MIR-30D, and MIR-30E).

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Additional file 4:

List of the top WGCNA generated correlations between significant transcription factors (nominal p < 0.01) and other significant genes (nominal p < 0.05) from the MPOA microarray. The blue module, which was correlated with the postpartum phenotype, is listed first and followed by the turquoise module.

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Additional file 5:

Primer sequences and annealing temperatures for all genes analyzed using real-time qPCR.

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