Different corticostriatal synaptic responses of direct and indirect striatal projection neurons do not depend on the cortical area stimulated. Corticostriatal suprathreshold synaptic responses were recorded after stimulus derived in the frontoparietal (A), temporal (B), and frontal (C) cortices (in sagittal or horizontal brain slices, schemes at left). It was observed that characteristic responses of dSPNs and iSPNs were maintained in any stimulated area, that is, the electrophysiological profile of each class was maintained. D: Voltage responses (top) to intracellular current steps (bottom) recorded in dSPNs (left) and iSPNs (right).
Vizcarra-Chacón et al. BMC Neuroscience 2013 14:60 doi:10.1186/1471-2202-14-60