Table 3

Number of En cells in brain and thoracic regions of WT and fru mutant CNSs
Anterior medial brain First thoracic ganglion (T1)
Genotype 28 hr APF 50 hr APF Adult 28 hr APF 50 hr APF Adult
WT male 47.2 ± 2.1 46.2 ± 2.2 48.4 ± 2.0 107.8 ± 3.5 118.8 ± 3.9 110.7 ± 7.1
(n = 16) (n = 9) (n = 14) (n = 10) (n = 10) (n = 10)
WT female 48.4 ± 1.3 35.2 ± 3.9a 50.7 ± 2.3 111.2 ± 3.2 117.6 ± 3.1 94.5 ± 5.3
(n = 19) (n = 10) (n = 10) (n = 10) (n = 10) (n = 10)
frusat15/fru4-40 male 44.5 ± 1.6 47.2 ± 2.5 42.2 ± 2.0 132.2 ± 4.9b 114.9 ± 3.3 89.3 ± 7.3
(n = 10) (n = 6) (n = 13) (n = 5) (n = 10) (n = 10)
frusat15/fru4-40 female 47.5 ± 2.5 36.5 ± 5.0 40.8 ± 1.6 121.2 ± 3.2 105.1 ± 3.7 103.0 ± 7.2
(n = 8) (n = 4) (n = 13) (n = 5) (n = 7) (n = 10)

The average number of En-positive neurons (mean ± SEM) found in anterior medial brain and T1 thoracic ganglia in WT and frusat15/fru4-40 mutant aged pupae and adults (n, refers to the number of brains analyzed with the hemispheres of the brain counted separately). Differences were analyzed by Kruskal-Wallis One-Way ANOVA followed by Dunn’s Method of Multiple Comparison for values within a given region.

a Significantly different from the mean number of 28 hr APF and adult WT male and female brain and 28 hr APF fru female medial brain neurons (p < 0.001).

b Significantly different from the mean number of adult WT female and fru male T1 neurons (p < 0.001).

Latham et al.

Latham et al. BMC Neuroscience 2013 14:57   doi:10.1186/1471-2202-14-57

Open Data