Table 5

Regression formula for hypotheses 3B
Regression formula for the effect of Occluding filament type on Mortality rate (hypothesis 3B)
Variable (reference category) Variable categories Regression coefficient 0.95 confidence interval for regression coefficient p-value
Constant NA 16.8 13.2 20.4 0.000
Occluding filament type (Uncoated) Silicon coated −1.2 −4.7 2.4 0.516
Poly-L-Lysine coated 3.0 −1.3 7.4 0.171
Other coatings −3.6 −9.0 1.8 0.188
Type of anesthetic (Inhalation anesthetic) Chloral Hydrate 5.0 0.57 9.4 0.027
Ketamine 3.1 −1.6 7.8 0.198
Barbiturates and bensodiazepines 6.6 −0.91 14.1 0.085
Other anesthetic 5.6 −0.04 11.2 0.052
Awakening of rats during occlusion (No) [Yes] 9.7 4.5 14.8 0.000
Heart rate monitoring (No) [Yes] −6.5 −10.8 −2.2 0.003
Type of infarct size evaluation (TTC) Radiology 13.3 6.5 20.1 0.000
Acidic/Basic stain or silver stain histology −1.2 −5.2 2.9 0.576
Immunohistology 10.8 1.6 20.0 0.022
Criteria for excluding rats (None) Observed absence of cerebral blood flow reduction −5.5 −8.6 −2.4 0.001
Lack of functional deficit .39 −3.5 4.2 0.843
Too small infarct −7.4 −14.2 -.56 0.034
Other pathology in animal −1.2 −5.3 2.9 0.577

Variables excluded by statistical software due to too low explanatory value: Strain, Sex, Elderly rats, Weight, Intubation, Temperature feedback system, Blood pressure monitoring, Blood gases/O2 saturation analyzed, Blood hemoglobin concentration analyzed, Blood glucose concentration analyzed, Postoperative antibiotics, Occlusion duration, Time after focal ischemia for evaluation of damage, Edema correction used, Blinding of infarct size determination procedure.

Ström et al.

Ström et al. BMC Neuroscience 2013 14:41   doi:10.1186/1471-2202-14-41

Open Data