Outline of the different experimental groups used in this study, namely Saline, Saline-NIr, MPTP, MPTP-NIr. The experimental time-line and behaviour time-points are shown. For the experimental time-line, there were two injections (saline or MPTP) and they occurred in the first 24 hrs. There were four NIr treatments (or not) and these occurred immediately after each injection and about 6 hrs later on the same. After the last NIr (and fourth) treatment, mice were allowed to survive for 6 days thereafter. There were four behavioural time-points; (T1) after first injection and NIr (or no) treatment; (T2) after second NIr (or no) treatment; (T3) after second MPTP or saline injection and third NIr (or no) treatment; (T4) after fourth NIr (or no) treatment.
Moro et al. BMC Neuroscience 2013 14:40 doi:10.1186/1471-2202-14-40