Examination of the relationships between AMPA/KA receptors, ROS and p38 MAPK. Rats were administered (A) NBQX (3 mg/kg, i.p.) or (B) edaravone (10 mg/kg, i.p.) at 1 hour before intraperitoneal administration of DA. Expression of p38 and phospho-p38 MAPK in rat hippocampus at 24 hours after intraperitoneal DA administration was analyzed by western blotting. *P < 0.05, **P < 0.01 and ***P < 0.001 (n = 3-7).
Tsunekawa et al. BMC Neuroscience 2013 14:4 doi:10.1186/1471-2202-14-4