Figure 3.

Etanercept decreased FPI-induced increases in the number of co-localization of microglia and TNF-α specific marker cells in ischemic white matter regions. Representative panel staining 72 h after FPI, respectively, for (A) a sham operation rat, (B) a FPI+saline rat and (C) a FPI+etanercept rat. (D) The FPI+saline group (▤) showed a significant increase in the number of co-localization of microglia and TNF-α specific marker cells in the ischemic white matter 72 h after FPI compared with the Sham controls (■) (*P < 0.01). The FPI+etanercept group (▩) showed a significant decrease in the number of co-localization of microglia and TNF-α specific marker cells in the ischemic white matter compared with the FPI+saline group (▤) (+P < 0.01). Each column and bar is the mean ± SD of eight rats per group.

Chio et al. BMC Neuroscience 2013 14:33   doi:10.1186/1471-2202-14-33
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