IGFBP-2 protein in adult mouse brain. IGFBP-2 is detectable in the olfactory bulb, cortex and cerebellum of adult mice. The olfactory bulb has the highest levels of IGFBP-2 compared to the rest of the tissue. (A) Western blot of IGFBP-2 in brain lysates. (Rcb - recombinant protein, OB - olfactory blulb, CTX - cortex, CB - cerebellum). (B) IGFBP-2 ELISA using brain lysates. Results are mean ± S.D. n = 5; *p < 0.001 by ANOVA, olfactory bulb versus cortex or cerebellum.
Fletcher et al. BMC Neuroscience 2013 14:158 doi:10.1186/1471-2202-14-158