Knockdown of itpr in neurons shows increased feeding. (A) Flies with pan-neuronal and peptidergic itpr knockdown show increased feeding as compared to the RNAi control as observed in their abdomen when fed colored food. (B) Spectrophotometric quantification of the red dye in fly abdomen (*p < 0.05; Student’s t test; difference significant as compared to the RNAi control). (C) Oil Red O staining for TAGs in the gut also shows increased accumulation of TAGs in the guts of flies with pan-neuronal and peptidergic knock down of itpr as compared to the RNAi control.
Subramanian et al. BMC Neuroscience 2013 14:157 doi:10.1186/1471-2202-14-157