Figure 5.

Immunocytochemical analysis of Ca2+-activated K+ channel and ETAR expressions in Ntg and GET-1 MCA after SAH. (A) Representative micrograph shows the localization and expression of Ca2+-activated K+ channel in the MCA of the Ntg and GET-1 after SAH. (n = 3 from each group of mice). Histogram shows the quantification results (relative value in percentage) of immunocytochemistry of sham and SAH of Ntg and GET-1 MCA sections. (*P < 0.05, **P < 0.01, ***P < 0.005, ANOVA followed by Bonferroni’s test; n = 3 for each group of mice). (B) Representative micrograph shows the localization and expression of ETAR in the smooth muscle cells (arrows) of MCA in Ntg and GET-1 mice. Histogram shows the quantification results (relative value in percentage) of immunocytochemistry of sham and SAH of Ntg and GET-1 MCA sections. (*P < 0.05, **P < 0.01, ANOVA followed by Bonferroni’s test; n = 3 for each group of mice). (C) Representative micrograph shows the immunocytochemical expressions of PKC-α and the diameters of MCA after treating with ETAR antagonist ABT-627. Histogram below shows the measurements of MCA diameter. (*P < 0.05, **P < 0.01, Mann-Whitey test; n = 3 for Ntg and GET-1 mice).

Yeung et al. BMC Neuroscience 2013 14:131   doi:10.1186/1471-2202-14-131
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