Table 4

Changes of grey matter volume, MTI, and DTI-values in patients with dystonia and their correlation with clinical data
Brain region Side BA MNI space t-value P (uncorr) Cluster size
x y z
Positive correlation UDRS and grey matter volume
Frontal gyrus right 11 1 22 −27 5.23 0.002 690
Cingulate gyrus left - −12 −19 31 4.81 0.004 310
Inferior frontal gyrus left - −45 27 6 3.97 0.022 134
Positive correlation UDRS and FA
Middle occipital gyrus right 19 36 −73 0 7.20 0.010* 1381
Cingulum, pars posterior right 30 13 −65 8 5.00 0.001* 2258
Occipital lobe, cuneus
17 9 −83 5 4.73
Occipital lobe left 19 −40 −66 −16 5.02 0.006 200
18 −2 −73 −6 4.70 0.011 495
Occipital lobe left 19 −36 −83 4 4.27 0.024 416
−27 −82 2 3.92
Frontal lobe left 10 −18 54 11 5.49 0.017* 1241
32 −23 40 8 4.32
11 −23 42 −1 4.11
Frontal lobe left 8 −23 18 37 4.92 0.007 386
Frontal lobe right 11 9 48 −16 4.72 0.010 161
Parietal lobe, precuneus left 7 −13 −74 49 4.34 0.021 210
Negative correlation UDRS and ADC
Occipital lobe, cingulum right - 19 −62 10 5.48 0.014* 1531
20 −73 14 4.20
28 −71 18 4.02
Middle occipital gyrus right 19 38 −72 5 4.14 0.026 412
Negative correlation disease duration and MTR
Middle frontal gyrus left 6 −26 23 60 5.65 0.001 559
Precentral gyrus left 4 −22 −28 64 4.99 0.002 549
Fusiform gyrus right 37 46 −56 −21 4.97 0.002 687
Negative correlation disease duration and FA
Superior frontal gyrus left 8 −26 20 54 5.89 0.001 255
Parietal lobe, precuneus left 7 19 −72 50 5.19 0.004 356
Parietal lobe, precuneus right 7 −4 −72 44 4.32 0.022 135
Occipital lobe left 17 −10 −92 −15 4.08 0.033 288
Temporal lobe left 37 −44 −45 −13 4.15 0.029 278
−40 −53 −10 3.79
Positive correlation disease duration and ADC
Occipital gyrus right 18 30 −94 −5 4.53 0.012 430
36 −91 −10 3.78
Occipital lobe. cuneus Right - 5 −99 4 4.16 0.025 246
Negative correlation disease duration and ADC
Middle frontal gyrus left 8 −26 15 52 6.34 <0.001 335
6 −41 −2 49 4.74 0.008 118
Middle frontal gyrus right 6 25 −12 64 4.26 0.021 118
Inferior parietal lobule right 40 40 −57 42 5.27 0.003 443
46 −51 53 3.71
Inferior parietal lobule right 40 38 −40 43 4.43 0.015 154
Inferior parietal lobule left 40 −50 −40 47 5.15 0.004 825
−40 −41 43 4.66
−44 −33 42 4.03
Postcentral gyrus right 3 25 −31 54 5.34 0.003 172
Postcentral gyrus left 3 −22 −30 63 4.80 0.008 614
Precentral gyrus right 4 55 −10 45 4.55 0.012 382
4 43 −14 59 4.24 0.022 283
Parietal lobe, precuneus left 7 −16 −63 55 4.28 0.020 155

* significant with FDR (false discovery rate).

Prell et al.

Prell et al. BMC Neuroscience 2013 14:123   doi:10.1186/1471-2202-14-123

Open Data