Table 2

Receptor protein levels in human cerebral arteries
Control Organ.Culture Organ Culture + treatment with U0126
ETB (%) ± s.e.m 100 ± 6 a 128 ± 3 a, b 80 ± 4 b
ETA (%) ± s.e.m 100 ± 4 a 137 ± 3 a, b 107 ± 4 b
TP (%) ± s.e.m 100 ± 3 119 ± 5 106 ± 3
AT1 (%) ± s.e.m 100 ± 2 a 62 ± 4 a 82 ± 7
AT2 (%) ± s.e.m 100 ± 2 a 120± 2 a 111 ± 1
5-HT1B (%) ± s.e.m 100 ± 6 a 128 ± 3 a, b 84 ± 4 b
pERK1/2 (%) ± s.e.m 100 ± 2 a 128 ± 2 a,b 86 ± 2 b

Activation of the different protein levels measured with immunohistochemistry in human arteries. Values are expressed as percentage of control and given as mean ± s.e.m. a = significant difference between organ culture and control groups, b = significant difference between organ culture and organ culture treated with U0126.

Ansar et al.

Ansar et al. BMC Neuroscience 2013 14:12   doi:10.1186/1471-2202-14-12

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