Figure 2.

Shh has trophic effects on motor neurons. Representative microscopic images show SMI32+ cells from WT mice treated with Shh 250 ng/ml had larger somata and more arborization (A) compared to cyclopamine-treated cells (B). It was shown that the average number of SMI32+ cells per field after treated with 250 ng/ml Shh was significantly higher than that control and cyclopamine (Shh 11 ± 1 vs control 5 ± 0, ** p = 0.0001; Shh 11 ± 1 vs cyclopamine 3 ± 0, * p = 0.0001; cyclopamine 3 ± 0 vs control 5 ± 0, δ p=0.017; C).

Ma et al. BMC Neuroscience 2013 14:119   doi:10.1186/1471-2202-14-119
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