Regional quantification of neuronal, microglial, astroglial, and oligodendroglial cells derived from dividing progenitors in control and striatal line mutant mice. Graphs showing the number of double-positive NeuN+/BrdU+, Iba1+/BrdU+, S100β+/BrdU+ and Olig2+/BrdU+ cells at specific sites relative to bregma in the M1 motor cortex (A-D), striatum (E-H) and periventricular (I-L) regions of the brain of mice belonging to the striatal line and control mice injected for 2 weeks with BrdU+ at 4 weeks of age and killed at age 8 weeks. There was a significant increase in the number of Iba1+/BrdU+ cells in the striatum and periventricular regions (both P< 0.001) in striatal mutant relative to control mice.
Smardencas et al. BMC Neuroscience 2013 14:111 doi:10.1186/1471-2202-14-111