Photomicrographs depicting p75 immunoreactivity of spinal cord sections in the lesion site after SCI. Endogenous p75 positive cells Schwann cells are present within the lesion site 2 weeks (A) and 4 months post injury (B). p75 positive profiles are present in large numbers in OEG (C-D) and Schwann cell (E-F) transplanted groups. The arrows in C and D represent DsRED-2 positive transplanted OEG within the lesion site co-mingled with host p75 positive Schwann cells. In the Schwann cell transplanted group the p75 positive endogenous Schwann cells (see arrows) also surround the transplanted DsRed-2 positive cells The Schwann cell transplants are tightly clustered unlike the dispersed OEG (see C-D). Scale bar in C (100 μm) also serves A and B.
Barbour et al. BMC Neuroscience 2013 14:106 doi:10.1186/1471-2202-14-106