Gene membership differences for the ‘immune’ module between networks. A) Visualization of the ‘immune’ module in the control network is depicted by taking 28 immune activation genes (GO:002253) form the module and their associated connections within the module. This resulted in a sub-module of 229 nodes and 672 edges. Immune activation genes are represented by the larger nodes on the outer ring, astrocyte marker genes are represented by the smaller nodes on the inner ring and ‘schizophrenia genes’ are represented by diamond shaped nodes. Lighter colored nodes indicate the gene is not present in the schizophrenia network immune module while darker colored nodes indicate the gene is retained. B) and C) Bar graphs were used to illustrate the difference in cell-type marker membership for the ‘immune’ module in the two networks (using the low-stringency list).
Mistry et al. BMC Neuroscience 2013 14:105 doi:10.1186/1471-2202-14-105