Email updates

Keep up to date with the latest news and content from BMC Neuroscience and BioMed Central.

This article is part of the supplement: Twenty First Annual Computational Neuroscience Meeting: CNS*2012

Open Access Poster presentation

Coherent spontaneous resting EEG of frontal regions in human brain

Shao-Wei Xue1, Yu-Qin Deng1 and Yi-Yuan Tang12*

Author Affiliations

1 Institute of Neuroinformatics, Dalian University of Technology, Dalian 116024, China

2 Texas Tech Neuroimaging Institute and Dept of Psychology, Texas Tech University, Lubbock, TX79409, USA

For all author emails, please log on.

BMC Neuroscience 2012, 13(Suppl 1):P25  doi:10.1186/1471-2202-13-S1-P25

The electronic version of this article is the complete one and can be found online at: http://www.biomedcentral.com/1471-2202/13/S1/P25


Published:16 July 2012

© 2012 Xue et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Poster presentation

Recent research has demonstrated that spontaneous brain activity is not random. At the level of large-scale brain systems, the ongoing activity measured with functional MRI reflects the organization of many highly coherent functional networks [1]. Synchronization likelihood is a general measure of the temporal correlation between two time series sensitive to linear as well as non-linear statistical interdependencies [2]. However, how to use synchronization likelihood to detect the EEG activity of brain regions is still not clear. In the present work, EEG data was obtained from 17 healthy subjects (10 males, mean age 22.9) at rest with the eyes closed. Functional connectivity between brain activities at different electrodes was estimated using the synchronization likelihood method at four bands respectively [3]: theta (4 - 8 Hz)、 alpha1 (8 - 10 Hz)、 alpha2 (10 - 13 Hz) and beta (13 - 30Hz). Following the previous study [4], individual electrodes were grouped into the six regions: frontal (FP1, FP2, F7, F3, Fz, F4, F8, AF7, AF3, AF4, AF8, F5, F1, F2, F6), central (FC5, FC1, FC2, FC6, C3, Cz, C4, FC3, FC4, C5, C1, C2, C6), parietal (CP1, CP2, P3, Pz, P4, CP3, CPz, CP4, P1, P2), left temporal (T7, CP5, P7, FT7, TP7, P5), right temporal (T8, CP6, P8, FT8, TP8, P6), and occipital areas (O1, Oz, O2, PO7, PO3, POz, PO4, PO8). We found that the frontal group had larger mean synchronization likelihood than any other group at each band, showing high coherent spontaneous EEG of human brain. Mean synchronization likelihood between groups had no these trends.

Conclusions

Synchronization likelihood could prove helpful for detection and estimation of functional relations between electrodes within and without brain regions.

Acknowledgements

This work was supported by the NSFC 60971096, Office of Naval Research and R21DA030066.

References

  1. Biswal B, Zerrin Yetkin F, Haughton VM, Hyde JS: Functional connectivity in the motor cortex of resting human brain using echo-planar mri.

    Magn Res Med 1995, 34:537-541. Publisher Full Text OpenURL

  2. Stam C, Van Dijk B: Synchronization likelihood: an unbiased measure of generalized synchronization in multivariate data sets.

    Physica D: Nonlinear Phenomena 2002, 163:236-251. Publisher Full Text OpenURL

  3. Micheloyannis S, Vourkas M, Tsirka V, Karakonstantaki E, Kanatsouli K, Stam CJ: The influence of ageing on complex brain networks: A graph theoretical analysis.

    Hum Brain Mapp 2009, 30:200-208. PubMed Abstract | Publisher Full Text OpenURL

  4. Freitas AL, Azizian A, Leung HC, Squires NK: Resisting recently acted-on cues: Compatibility of Go/NoGo responses to response history modulates (frontal P3) event-related potentials.

    Psychophysiology 2007, 44:2-10. PubMed Abstract | Publisher Full Text OpenURL