Figure 5.

The effect of gonadectomy and sex steroid replacement on sex steroid receptor mRNA expression in adolescent male rat substantia nigra.(A) AR mRNA levels were increased by T, DHT and E compared to Intact (*) and Gdx (#) groups (n=12-14/group). (B) ERα mRNA was decreased by DHT replacement compared to the Intact group. T and E did not change ERα mRNA levels and were significantly different to the DHT treated group. (C) ERβ mRNA was increased by T (compared to Intact and Gdx groups) and by DHT (compared to Gdx only), but not by E. *=p < 0.05, **=p < 0.01, *** and ###=p < 0.0001.

Purves-Tyson et al. BMC Neuroscience 2012 13:95   doi:10.1186/1471-2202-13-95
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