An anterior-posterior slow spindle gradient was present, but attenuated in OSA patients, in comparison to non-OSA subjects. For Moderate OSA, slow spindle percentage was reduced in centro-parietal, but not in frontal regions as the night progressed. In contrast, non-OSA subjects showed reduced slow spindle percentages in frontal as well as centro-parietal regions across the night.
Schönwald et al. BMC Neuroscience 2012 13:89 doi:10.1186/1471-2202-13-89