Doublecortin-immunoreactive (DCX+) cells in representative cortical areas from a Pb-treated (right panels) and an age-matched control (left panels) guinea pigs surviving 4 months. The amount of DCX + cells are noticeably reduced in the parietal (A, B), temporal (C, D) and frontal (E, F) cortices in the Pb treated animal relative to control. Inserts are enlarged to illustrate DCX + cells with varying sizes and morphologies. Scale bar in (A) = 200 μm applying to main image panels, equivalent to 100 μm for inserts.
Huang et al. BMC Neuroscience 2012 13:82 doi:10.1186/1471-2202-13-82