Selenium reduces DNA oxidatioin. A. A set of representative anti-8-OHdG immunofluorescent stained images (green) shows decline in 8-OHdG fluorescence signal at 24 h of recirculation in selenium pretreated as compared to saline treated. Blue color (DAPI) denotes nuclei. B. Bar graph shows the number of 8-OHdG positive cells per section in the cortex area of the brain. Data are presented as mean ± SD. *P < 0.05. Se = selenium and Cont = control. Bar = 100 μm.
Mehta et al. BMC Neuroscience 2012 13:79 doi:10.1186/1471-2202-13-79