Figure 7.

Erythropoietin treatment prevents IH-induced anxiety in mice. (A). Mice exposed to IH and treated with vehicle (IH-C) spend significantly less time in the open arm of the elevated plus maze compared to IH-EPO, RA-EPO, or RA-C mice (n = 18/experimental group;*-p < 0.001). (B). A reduced number of closed-arm entries emerged in mice exposed to IH and treated with vehicle (n = 18/experimental group;* - p < 0.001). (C). Time spend in the Center Area was increased in mice exposed to IH and treated with vehicle (n = 18/experimental group;* - p < 0.001).

Dayyat et al. BMC Neuroscience 2012 13:77   doi:10.1186/1471-2202-13-77
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