Table 4

Functional Activations for High-Calorie, Low-Calorie and Non-Food Object ContrastsPost-Treatment vs. Baseline (Pre-Treatment)in Obese Endometrial Cancer Patients in a 16-Session Behavioral Lifestyle Intervention
   Brain Region (Hemisphere) Pre-Meal (Fasted) Post-Meal (Fed/Satiated)
Peak Voxel Peak Voxel
x y z Cluster Size* t x y z Cluster Size* t
POST < PRE TREATMENT
    High Calorie vs. Low Calorie Food
   No regions survived threshold
    High Calorie vs. Non-Food Object
   Superior Frontal Gyrus (BA = 6) 38 39 30 416 -4.72
   Lateral Globus Pallidus 20 -13 6 972 -9.45
   Cingulate Gyrus (BA = 31) -9 -23 34 968 -6.63
   Thalamus -14 -24 5 738 -5.63
   Posterior Cingulate (BA = 29) -8 -45 16 583 -6.52
   Precuneus (BA = 31) -16 -44 30 811 -5.85
   Claustrum 37 -6 6 911 -6.62
    Low Calorie vs. Non-Food Object
   Insula (Bilateral; L; BA = 13) 38 -22 11 613 -5.44
   Insula (Bilateral; R; BA = 13) -40 -13 14 691 -6.64
   Precentral Gyrus (BA = 4) -52 -12 24 963 -10.6
   Middle Temporal Gyrus (BA = 39) -39 -50 6 568 -4.73
POST > PRE TREATMENT
    High Calorie vs. Low Calorie Food
   Superior Temporal Gyrus (BA = 22) -48 11 -5 758 5.72
   Superior Frontal Gyrus (BA = 10) 21 63 27 607 5.90
    High Calorie vs. Non-Food Object
   No regions survived threshold
    Low Calorie vs. Non-Food Object
   No regions survived threshold

x, y, z = coordinates in Talairach space; t statistic for peak voxel; *Cluster size is reported in mm3. Results are whole brain cluster corrected for multiple comparisons; threshold α < 0.05 (min cluster size: 15–36 voxels).

Nock et al.

Nock et al. BMC Neuroscience 2012 13:74   doi:10.1186/1471-2202-13-74

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