Table 3

Functional Activations for High-Calorie, Low-Calorie and Non-Food Object Contrasts atPost-Treatmentin Obese Endometrial Cancer Patients Enrolled in a 16-Session Group Behavioral Lifestyle Intervention
   Brain Region (Hemisphere) Pre-Meal (Fasted) Post-Meal (Fed/Satiated)
Peak Voxel cPeak Voxel
x y z Cluster Size* t x y z Cluster Size* t
↑ Activation
    High Calorie vs. Low Calorie Food
   Declive -48 -83 -20 457 8.70
   Declive -19 -64 -9 233 4.87
   Inferior Frontal Gyrus (BA = 46) 44 38 12 907 8.97
   Middle Frontal Gyrus (BA = 9) 41 18 31 575 9.75
   Middle Frontal Gyrus (BA = 10) 40 62 8 479 12.5
   Anterior Cingulate (BA = 32) -16 44 -4 403 7.63
   Insula (BA = 13) 42 11 0 182 5.94
    High Calorie vs. Non-Food Object
   Culmen (BA = 10) -4 -57 2 196 5.04
   Middle Frontal Gyrus (BA = 6) -53 7 44 171 4.60
    Low Calorie vs. Non-Food Object
   No regions survived threshold
↓ Activation
    High Calorie vs. Low Calorie Food
   Medial Frontal Gyrus (BA = 10) 5 55 12 292 -9.68
    High Calorie vs. Non-Food Object
   Precentral Gyrus (BA = 4) 48 -6 42 379 -4.86
   Caudate Tail 18 -37 20 735 -10.7
   Claustrum 29 -20 16 492 -7.36
    Low Calorie vs. Non-Food Object
   Culmen 9 -58 -8 457 -7.76
   Declive 22 -60 -13 680 -8.40
   Cingulate Gyrus (BA = 31) -8 -23 43 672 -11.6
   Postcentral Gyrus (BA = 3) -56 -10 22 701 -15.3
   Insula (BA = 13) -34 -15 21 839 -11.3
   Anterior Cingulate (BA = 24) -9 32 13 516 -8.84
   Medial Frontal Gyrus (BA = 10) -7 55 12 640 -8.46

x, y, z = coordinates in Talairach space; t statistic for peak voxel; *Cluster size is reported in mm3. Results are whole brain cluster corrected for multiple comparisons; threshold α < 0.05 (min. cluster size: 6-38 voxels).

Nock et al.

Nock et al. BMC Neuroscience 2012 13:74   doi:10.1186/1471-2202-13-74

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