Table 2

Functional Activations for High-Calorie, Low-Calorie and Non-Food Object Contrasts atBaselinein Obese Endometrial Cancer Patients Enrolled in a 16-Session Group Behavioral Lifestyle Intervention
  Brain Region (Hemisphere) Pre-Meal (Fasted) Post-Meal (Fed/Satiated)
Peak Voxel Peak Voxel
x y z Cluster Size* t x y z Cluster Size* t
↑ Activation
    High Calorie vs. Low Calorie Food
   Insula (BA = 13) 44 -11 18 524 5.67
   Cingulate Gyrus (BA = 31) 22 -21 44 491 6.04
   Precentral Gyrus (BA = 4) 53 -4 15 422 5.49
    High Calorie vs. Non-Food Object
   OFC (Bilateral; BA = 47) -47 32 -7 839 14.5
   Medial Frontal Gyrus (BA = 6) -9 28 37 897 11.6
   Anterior PFC (BA = 10) -8 56 19 825 10.4
   Dorsolateral PFC (BA = 9) -42 3 28 994 10.4
   Dorsolateral PFC (BA = 46) 45 32 11 937 7.93
   Middle Frontal Gyrus (BA = 8) -39 26 42 648 8.27
   Thalamus (Bilateral) 9 -16 3 847 5.00
   Posterior Cingulate (BA = 29) -7 -45 18 491 5.24
   Precuneus (BA = 7) -24 -77 47 535 7.65
    Low Calorie vs. Non-Food Object
   Putamen -24 0 16 756 9.35
   Claustrum 24 12 15 830 9.89
   Caudate -8 7 14 783 7.64
   Caudate 13 -2 17 296 5.17
   Anterior PFC (BA = 10) -32 64 4 635 8.70
   Superior Frontal Gyrus (BA = 8) -22 19 46 517 8.03
↓ Activation
    High Calorie vs. Low Calorie Food
   Anterior Cingulate 21 39 15 766 -10.9
    High Calorie vs. Non-Food Object
   No regions survived threshold
    Low Calorie vs. Non-Food Object
   Culmen 22 -47 -12 639 -6.72

x, y, z = coordinates in Talairach space; t statistic for peak voxel; *Cluster size is reported in mm3. Results are whole brain cluster corrected for multiple comparisons; threshold α < 0.05 (min. cluster size: 10-36 voxels).

Nock et al.

Nock et al. BMC Neuroscience 2012 13:74   doi:10.1186/1471-2202-13-74

Open Data