Table 2

Top 25 genes in RMC based on fold change. Both MATLAB and GeneSpring analysis are represented
Genes from MATLAB analysis Genes from Genespring analysis
Gene Symbol Gene Title Fold Change Function Gene Symbol Gene Title Fold Change Function
Mobp myelin-associated oligodendrocyte basic protein 623.18 nervous system development Mog myelin oligodendrocyte glycoprotein 26.34 cell adhesion
Mog myelin oligodendrocyte glycoprotein 39.14 cell adhesion Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 24.41 antigen processing and presentation
Mbp myelin basic protein 21.57 myelination Mbp myelin basic protein 22.86 myelination
Robo3 roundabout homolog 3 (Drosophila) 17.39 neuron migration Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 19.31 sensory perception of smell
Mal mal, T-celldifferentiation protein 16.13 intracellular protein transport Opalin oligodendrocytic myelin paranodal and inner loop protein 15.59 Golgi apparatus
Dnah12 dynein, axonemal, heavy polypeptide 12 12.77 microtubule-based movement Plp1 proteolipid protein 1 12.00 glial cell differentiation
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 12.34 antigen processing and presentation Camk2a calcium/calmodulin- dependent protein kinase II alpha 9.59 G1/S transition of mitotic cell cycle
Hapln2 hyaluronan and proteoglycan link protein 2 9.84 cell adhesion Lgi4 leucine-rich repeat LGI family, member 4 9.39 neuron maturation
Plp1 proteolipid protein 1 9.00 glial cell differentiation Cpne9 copine family member IX 8.71 unknown
Ermn ermin, ERM-like protein 8.82 morphogenesis of a branching structure Znf76 zinc finger protein 76 (expressed in testis) 8.55 transcription
Tnnc2 troponin C type 2 (fast) 8.60 skeletal muscle contraction Rhpn1 rhophilin, Rho GTPase binding protein 1 8.35 signal transduction
Mag myelin-associated glycoprotein 8.12 cell adhesion Gng13 guanine nucleotide binding protein (G protein), gamma 13 8.16 G-protein coupled receptor protein signaling pathway
Lgi4 leucine-rich repeat LGI family, member 4 8.10 neuron maturation Mag myelin-associated glycoprotein 7.99 cell adhesion
Extl1 exostoses (multiple)-like 1 8.09 protein binding Herc6 hect domain and RLD 6 7.71 protein modification process
Aldh3b1 aldehyde dehydrogenase 3 family, member B1 7.81 cellular aldehyde metabolic process Chn1 Chimerin (chimaerin) 1 6.31 signal transduction
Hhatl hedgehog acyltransferase-like 7.79 negative regulation of N-terminal protein palmitoylation Sept4 septin 4 5.81 cell cycle
Gng13 guanine nucleotide binding protein (G protein), gamma 13 7.44 G-protein coupled receptor protein signaling pathway Ccdc37 coiled-coil domain containing 37 5.66 unknown
Akap8l A kinase (PRKA) anchor protein 8-like 7.30 DNA binding Cmtm5 CKLF-like MARVEL transmembrane domain containing 5 5.30 membrane
Cpne9 copine family member IX 7.24 Unknown Amhr2 anti-Mullerian hormone receptor, type II 5.08 protein amino acid phosphorylation
Car12 Carbonic anyhydrase 12 7.21 one-carbon metabolic process Sptbn4 spectrin, beta, non-erythrocytic 4 4.84 axonogenesis
Srpk3 SFRS protein kinase 3 7.11 protein amino acid phosphorylation Gsta3 glutathione S-transferase A3 4.55 glutathione metabolic process
Casc1 cancer susceptibility candidate 1 6.90 Unknown Grin2c glutamate receptor, ionotropic, N-methyl D-aspartate 2 C 4.53 startle response
S1pr5 sphingosine-1-phosphate receptor 5 6.82 signal transduction Fah fumarylacetoacetate hydrolase 4.50 arginine catabolic process
Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) 6.75 carbohydrate metabolic process Ggn gametogenetin 4.49 multicellular organismal development
Itsn2 intersectin 2 6.67 regulation of Rho protein signal transduction Ntsr2 neurotensin receptor 2 4.13 signal transduction

Parakalan et al.

Parakalan et al. BMC Neuroscience 2012 13:64   doi:10.1186/1471-2202-13-64

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