Differences in brain structure and body weight of WT and cD2KO mice. Estimations of the total (bilateral) volume of brain (A), hippocampus (B) and the dentate GCL (C) reveal substantial reduction of these structures due to the lack of functional cD2 (*p < 0.001). Differences are already apparent at P35. (D) The body weight of cD2KO mice is similar to that of WT litters, except at an age of P288 (*p < 0.01). Statistical significance is only marked for genotype-specific differences.
Ansorg et al. BMC Neuroscience 2012 13:46 doi:10.1186/1471-2202-13-46