Escape latency during Morris water maze testing. Escape latency was measured in p50 mice during the acquisition phase, where both groups significantly decreased (P < 0.001) their escape latency times over 7 days of testing (p50+/+: from mean 36 s to 20 s; p50−/− mean 46 s to 14 s), but there was no statistical difference (P = 0.39) between p50−/− and p50+/+ mice over the 7 day period. A trend is seen on day 3 where p50−/−mice show shorter escape times.
Oikawa et al. BMC Neuroscience 2012 13:45 doi:10.1186/1471-2202-13-45