Table 1

Clinical parameters of EAE experiments in SJL/J mice and DA rats (*, p < 0

Incidence Mortality

Disease onset [d] ± StdDev

Cumulative score ± StdDev

Mean maximal score ± StdDev


SLPI immunization in passive EAE of SJL/J mice


SLPI-immunized mice

10/10

0/10

23.0 ± 4.6 *

8.9 ± 4.6 *

2 ± 0.5


OVA-immunized mice

7/7

0/7

17 ± 2.8

21.4 ± 7.5

2.6 ± 0.7


SLPI immunization in active EAE of DA rats


SLPI-immunized rats

7/8

1/8

20.9 ± 10.8

21.2 ± 19.3

2.8 ± 2.0 *


OVA-immunized rats

8/8

3/8

13.8 ± 1.8

30.7 ± 9.3

4.5 ± 0.8


SLPI administration in active EAE of SJL/J mice


SLPI-treated mice

6/7

1/7

11.1 ± 2.4 *

29.7 ± 15.3

3.1 ± 1.5


saline-treated mice

5/5

0/5

15.2 ± 4.4

19.8 ± 5.7

2.8 ± 0.4


Müller et al. BMC Neuroscience 2012 13:30   doi:10.1186/1471-2202-13-30

Open Data