Table 2

Morphometric parameters of proximal and distal segments of the sural nerve fascicles of male and female WKY and SH

Female

WKY

Male

WKY

Female

SHR

Male

SHR

Female

WKY

Male

WKY

Female

SHR

Male

SHR


Proximal Segments

Distal Segments


FA (μm2)

49096 ± 3140

52479 ± 3052

51596 ± 2484

54504 ± 3062

38162 ± 2635*

41188 ± 3998

44956 ± 4812*

50144 ± 4272

Fascicle Ø (μm)

193 ± 16

181 ± 22

205 ± 14

184 ± 15

89 ± 4*

113 ± 20

146 ± 9*#

155 ± 15#

MF number

871 ± 25

831 ± 47

889 ± 36

884 ± 33

746 ± 47*

725 ± 53

690 ± 47*

688 ± 45

MFD (fibers/μm2)

18469 ± 1072

15986 ± 724

17454 ± 715

16541 ± 647

19849 ± 821

18119 ± 1059

16370 ± 972#

14770 ± 1586#

SCN number

40 ± 3

42 ± 5

35 ± 4

35 ± 2

33 ± 2

35 ± 3

35 ± 5

27 ± 2

SCND (nuclei/μm2)

843 ± 58

810 ± 100

731 ± 84

666 ± 48

906 ± 83

889 ± 60

800 ± 68#

576 ± 78#

MF occupancy (%)

38.79 ± 1.46

36.90 ± 1.65

40.10 ± 1.82

41.30 ± 2.96

40.15 ± 1.56

39.80 ± 1.99

35.75 ± 1.62

35.09 ± 3.01

CP occupancy (%)

0.96 ± 0.26

0.90 ± 0.22

0.40 ± 0.13

0.55 ± 0.09

0.71 ± 0.19

0.69 ± 0.13

0.18 ± 0.06#

0.28 ± 0.12#


Data expressed as mean ± standard error of mean (SEM). FA = fascicle area, Ø = diameter, MF = myelinated fiber, MFD = myelinated fiber density, SCN = Schwann cell nuclei, SCND = Schwann cell nuclei density, CP = capillary. * indicates differences between proximal and distal segments (paired Student's t-test p < 0.05); # indicates differences between WKY and SHR (unpaired Student's t-test, p < 0.05)

Sanada et al. BMC Neuroscience 2012 13:24   doi:10.1186/1471-2202-13-24

Open Data