ATX attenuates the generation of intracellular ROS by MPP+-induced oxidative stress in PC12 cells. PC12 cells treated groups: Data.01: Negative control without DCFH-DA; Data.02: Positive control with Rosup; Data.03: control; Data.04: MPP+ (500μM); Data.05: MPP+ (500μM) and ATX (5μM); Data.06: MPP+ (500μM) and ATX (10μM); Data.07: MPP+ (500μM) and ATX (20μM); Data.08: ATX (10μM); Data.09: MPP+ (500μM) and DPI (1μM). Intracellular ROS generation was determined by DCFH-DA fluorescence.
Ye et al. BMC Neuroscience 2012 13:156 doi:10.1186/1471-2202-13-156